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More than 10 years of clinical success using AlloDerm® Regenerative Tissue Matrix in septal perforation repair1
“Acellular human dermal grafts can be used as connective tissue interpositional grafts in the repair of septal perforations with success rates similar to the use of temporalis fascia, mastoid periosteum, or pericranium. One distinct advantage is the absence of donor-site morbidity. In addition, this graft material is thicker and easier to place and suture and may give more substance to the repaired septum.”1
For additional information, please refer to full article.1
An innovative technique for septal perforation repair using AlloDerm® Regenerative Tissue Matrix
AlloDerm® Tissue Matrix may provide surgeons with a useful tool for septal perforation repairs. In situations involving a three-layer septal defect (cartilage and right and left mucosa), surgeons may consider using AlloDerm® Tissue Matrix as an interpositional graft placed between the repaired mucoperichondrial flaps to provide connective tissue support. Due to its biomechanical strength, it can provide a strong repair and excellent coverage capability in cases where autologous tissue is either not available or not desirable.
AlloDerm® Tissue Matrix has been used in a variety of soft-tissue repair procedures in more than one million grafts and implants to date. As shown in animal studies, it supports tissue regeneration by allowing rapid revascularization, white cell migration and cell repopulation2, which can minimize the risk of infection of the implant. Ultimately it transitions into host tissue for a strong, natural repair. AlloDerm® Tissue Matrix is derived from natural tissue which is processed using a proprietary technique to remove the cells that can lead to tissue rejection and graft failure. The resulting acellular tissue matrix is strong, optimizing outcomes for soft-tissue repair procedures, including ENT applications, challenging hernia repair and breast reconstruction post-mastectomy.
References:- Russell WH Kridel, MD, et al. Septal perforation repair with acellular human dermal allograft. Arch Otolaryngol Head Neck Surg. 1998;124:73-78.
- Connor J, et al. Retention of structural and biochemical integrity in a biological mesh supports tissue remodeling in a primate abdominal wall model. Regenerative Medicine. 2009 (in press).
Before use, physicians should review all risk information and essential prescribing information which can be found in the AlloDerm® Regenerative Tissue Matrix Instructions for Use. |
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